Karisma: The new generation of biostimulation with human collagen for natural facial rejuvenation

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Karisma

The passage of time inevitably leaves its marks on the face. The production of collagen and elastin gradually decreases, the skin loses its firmness, fine lines become more pronounced and tissues begin to relax. In recent years, aesthetic medicine has turned to treatments that do not simply aim at temporarily correcting wrinkles, but at activating the body's natural regeneration mechanisms.

Karisma is one of the most modern developments in the field of biostimulation. It is an innovative injectable biomaterial that activates fibroblasts and stimulates the natural production of new collagen, offering gradual skin renewal with a completely natural result.

Unlike treatments that simply fill wrinkles or increase facial volume, Karisma aims to improve skin quality and restore its structure from the inside out.


What is Karisma?

Karisma is an advanced, next-generation biostimulating implant, specifically designed for skin regeneration and rejuvenation.

Its composition is based on three key ingredients:

  • Recombinant human collagen type I (Rh Collagen)
  • High purity hyaluronic acid
  • Carboxymethylcellulose (CMC)

This combination creates an ideal environment for the activation of fibroblasts, the cells responsible for the production of collagen and elastin.

So, instead of temporarily covering the signs of aging, it contributes to the natural reconstruction of the skin.

How does Karisma work?

Over time, collagen production decreases significantly. The skin becomes thinner, less elastic and gradually loses its firmness.

Karisma works by activating the body's natural regeneration mechanisms.

After application:

  • fibroblasts are activated,
  • the production of new collagen is stimulated,
  • skin density improves,
  • elasticity increases,
  • natural hydration is enhanced,
  • Tissue quality is gradually restored.

Regeneration occurs progressively, resulting in the improvement appearing natural and not artificial.


What problems might it face?

Karisma can be applied to people who present with:

  • facial relaxation,
  • loss of elasticity,
  • fine and moderate wrinkles,
  • dull and tired appearance,
  • dehydrated skin,
  • loss of density,
  • photoaging,
  • early signs of aging.

It is also applied at younger ages as a preventative measure, before collagen loss becomes severe.


Is the treatment painful?

The treatment is characterized by very good tolerance.

Most patients feel only a slight sting during application.

Where necessary, local anesthetic cream is used to make the procedure even more comfortable.


After treatment

Immediately afterwards, the following may appear:

  • mild redness,

  • small swelling,

  • light sensitivity,

  • small bruises at the injection sites.

These phenomena are normal and subside within a few hours or days.

Recommended:

  • avoiding strenuous exercise for 24 hours,

  • avoiding saunas and very high temperatures,

  • use of sunscreen,

  • good hydration of the body.


When are the results visible?

The improvement is taking place gradually.

A first image is usually visible within the first few weeks due to the hydration provided by hyaluronic acid.

However, true regeneration progresses progressively as the production of new collagen is activated.

The final result becomes apparent approximately 2 to 3 months after the completion of the treatment protocol.


How long does the result last?

The duration depends on:

  • the age,

  • the quality of the skin,

  • lifestyle,

  • smoking,

  • solar exposure,

  • proper skin care.

In most patients, the results last for approximately 12 to 18 months.


How many sessions are needed?

The treatment protocol is personalized.

Two or three sessions are usually recommended, spaced a few weeks apart.

A maintenance session can then be performed depending on the patient's needs.


Can it be combined with other treatments?

Yes.

Karisma can be combined with many aesthetic treatments such as:

  • botulinum toxin,

  • hyaluronic acid,

  • PRP,

  • mesotherapy,

  • fractional laser,

  • radio frequencies,

  • thread lifting.

The right combination allows for even more complete facial rejuvenation.


Are there any side effects?

Karisma is characterized by a high safety profile when applied by a qualified physician.

Serious complications are extremely rare.

The most common reactions are transient and include:

  • redness,

  • edema,

  • small bruises,

  • sensitivity in the application area.


 

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With proper planning, a personalized approach and selection of appropriate treatments, a natural result can be achieved that restores body proportions and contributes substantially to improving self-confidence and quality of life.

In which areas does it apply?

Karisma can be used on many areas of the face and body.

Most commonly applied:

  • face,
  • cheekbones,
  • cheeks,
  • facial contour,
  • neck,
  • neckline,
  • back of the hand.

In selected cases, it can also be used to improve scars or areas with poor skin quality.

 

Who are the suitable candidates?

The treatment is aimed at women and men who desire natural rejuvenation without altering their facial features.

Ideal candidates are those who:

  • show mild to moderate relaxation,
  • they notice a decrease in elasticity,
  • want to improve skin quality,
  • looking for a natural result,
  • do not want excessive volume from fillers,
  • They are in good general health.

 

Does it need any preparation?

The treatment does not require any special preparation.

The doctor may recommend:

  • avoiding anticoagulant or anti-inflammatory drugs where permitted,

  • avoiding alcohol in the previous 24 hours,

  • Avoiding intense sun exposure before treatment.

Instructions are personalized depending on each patient's history.

 

Karisma: The treatment process in detail

The treatment is performed in the doctor's office and does not require hospitalization.

Initially, the area is thoroughly cleaned and disinfected.

If necessary, local anesthetic cream is applied to make the procedure as comfortable as possible.

The plastic surgeon then injects Karisma with a very fine needle or special microcannula, depending on the area to be treated.

The material is evenly distributed throughout the tissues with the aim of activating natural regeneration mechanisms.

The duration of the treatment usually ranges from 20 to 40 minutes.

Upon its completion, the patient can immediately return to their daily activities.

 

The advantages of an integrated approach

  • Personalized treatment plan.

  • Complete restoration of post-pregnancy changes.

  • Natural aesthetic result.

  • Improvement of body proportions.

  • Boosting self-confidence.

  • Option to combine multiple treatments when indicated.

 

frequently asked questions

Is it filler?

No. Karisma does not work as a classic filler. Its goal is to biostimulate and naturally produce new collagen.

Will my expression change?

No. The treatment does not alter facial features but gradually improves skin quality.

From what age can it be applied?

There is no specific age limit. It is usually applied after the age of 30, when natural collagen production begins to decrease.

When can I return to work?

In most cases immediately after treatment.

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